I am working on being more direct and concise, please bear with me,
@stefano.menci referenced HIPAA compliance as an elaborative use case, I merely attempted to provide an actionable approach. I did try and include in my post most of the issues that the original asker had, with a specific focus on that use case (was fun!).
The Solved Answer provided by @joinlook is not very informative, although I do somewhat agree with the sentiment.
I did however, stumble upon a very satisfactory and verbose answer to the main question; “Anyone know a web framework for Python?”, but I don’t think anyone would find it helpful. (Verbose and extensive installations)